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October 16, 2008 Raimi told MTV that he’d “love to work with Dunst again” but added “I hope she’ll be written into it. I couldn’t imagine making one without her, and I think she’s an important part of the movies.”

“I don’t have a script yet, but production would start probably by March of 2010, I’m guessing,” the director explained. “It sounds like a long time away, but we need a script first, and a lot of pre-production has to take place.” He added that no decision has been made yet about shooting Spider-Man 4 and 5 back-to-back, and stressed that studio boss Amy Pascal would make the final decision regarding the shooting schedule.

Raimi was coy about whether Dylan Baker, who has appeared in the last three installments as Dr. Curt Connors, would finally appear as the villainous Lizard. Raimi said that they “just don’t know who the villain is yet,” but suggested that the storylines for the fourth and fifth films would most likely be intertwined.